With an intuitive touch-screen interface and a large field of view, you can view your cells, capture high-resolutions images and perform multichannel merges with ease.
No dark room, no training, no overwhelming user interface.
With thoughtful features like an integrated light shield and an intuitive touch-screen, ZOE™ provides the flexibility to carry out fluorescent cell imaging at your bench, right where you work. Combining bright-field capabilities with multi-channel fluorescence, this cell imager is both affordable and easy to use – your perfect solution for routine cell culture and imaging applications.
Both you and your students can take ZOE™ for a test drive. Just launch the ZOE™ Interactive Web App to try the intuitive ZOE™ user interface, manipulate images, view features and specifications in depth, and more.Launch Web App
Brightfield and three fluorescence channels*
*High-quality hard-coated filter sets provide high light transmission and long life.
Ultraviolet (UV) LED for blue channel
Blue LED for green channel
Green LED for red channel
Ring of green LEDs for brightfield channel (reduces chromatic aberration)
Excitation: 355/40 nm; emission: 433/36 nm
Excitation: 480/17 nm; emission: 517/23 nm
Excitation: 556/20 nm; emission: 615/61 nm
25.6 cm (10.1 in.) color LCD monitor, touch screen with antiglare and antifingerprint treatment, 1,280 x 768 pixels image resolution, 80–180° angle tilt range
Coarse and fine, manual adjustment
Monochrome camera, 12 bit CMOS, 5 megapixels
6 mm travel in X, Y direction; touch-screen control of travel speed and direction
Flasks (T25, T75, T225); multiwell plates (6, 12, 24, 48, 96, and 384 wells); dishes (35, 60, and 100 mm); chamber slide; glass microscopy slide
JPEG, TIFF, RAW
Images from up to 4 channels can be overlaid
16 GB internal memory (~2,500 JPEG files, 1,500 TIFF files, 400–800 RAW files)
Yes, 2 USB ports
Yes, through HDMI port
Yes, Android operating system; PC is not required for operation
33 x 32 x 30 cm (13 x 12.6 x 11.8 in.)
9 kg (19.8 lb)
Yes, with its integrated light shield fluorescence imaging can be done anywhere in the lab.
You can download a complete list of compatible fluorophores here.)
ZOE's™ large open stage is compatible with all cell culture vessel types without any adaptors.
While ZOE™ does not have phase contrast hardware, it uses green colour LEDs (for reduced chromatic aberration) and oblique illumination to achieve phase like image contrast.
You can download the latest version of the ZOE firmware here.
Integrated light shield enables fluorescence imaging in ambient light, dark room is not needed.
Yes, the objective lens is located below the stage, thus making imaging samples in cell culture vessels possible.
Yes, ZOE has integrated digital camera (monochrome 12 bit CMOS, 5 megapixels) that is controlled through touch screen. Captured images are stored in 16GB internal memory.
The images files (JPEG, TIFF, or RAW) are compatible with commonly used imaging software packages.
LEDs are used as light sources for both brightfield and fluorescent channels. Unlike mercury arc lamps, that need to be replaced approximately every 300 hours, LEDs provide thousands of hours of illumination that are instantly ready for use after power on, without any warm up time. The intensity of the light emitted by the LEDs is user adjustable, thus reducing sample photo-bleaching.
ZOE™ is fully integrated and its fluorescence channels are optimized for commonly used fluorescent proteins and dyes. While not offering the ultimate flexibility of filter/light source selection, a large number of fluorophores is compatible with ZOE™ giving user a large degree of flexibility and choice of fluorophores – allowing them to do three color fluorescence experiments in an easy to use and affordable instrument format.
Focus position indicator (upper left side) shows the Z axis position number; the number is updated during focusing. Knowing the approximate Z number for the tissue culture vessels you use can speed up focusing.
|Vessel Type||Z Axis Position|
|Microscope slide||720 (± 100)|
|6-well slide||2,000 (± 100)|
|12-well slide||2,200 (± 100)|
|24-well slide||1,900 (± 100)|
|48-well slide||2,000 (± 100)|
|96-well slide||3,500 (± 200)|
|T25 flask||1,800 (± 200)|
|T75 slide||2,500 (± 200)|
|T225 tissue culture flask||3,200 (± 200)|
|Small petri dish||1,200 (± 200)|
|Large petri dish||100 (± 200)|
The system could be damaged if anything in ZOE™ cell imager was deleted (images, folders) through the PC or if anything was copied (images, programs) into the ZOE™ cell imager through the PC.
Images not exported through the USB port will be monochrome, the pseudo-coloring of images from fluorescent channels occurs when exported through USB port.
Yes, it can be connected through the HDMI port in the back of the instrument. Note: Not all adaptors used for projectors/monitors without HDMI port are compatible with ZOE firmware. If upon connection the cell imager can not exit the loading screen then the adaptor is not compatible.
There are no calibration requirements, the ZOE™ cell imager is factory calibrated.